Medicinal chemistry

For the development of innovative drugs, referencematerials are indispensable for performing the necessary pharmacokinetic studies. It is not uncommon for projects to be significantly delayed or even fail because the required reference standards of active ingredients, metabolites, by-products or impurities are not available quickly enough. Initial test compounds for "hit finding" are either provided from our internal stock or exclusively synthesized. Subsequent hit-to-lead studies and lead optimizations are performed by further chemical structure modifications to increase potency, selectivity, bioavailability and to improve the safety profile.

That is why Endotherm Life Science Molecules supports research-based pharmaceutical companies in the discovery and development of new drugs by independently developing syntheses of the necessary referencematerials. This enables your projects to move quickly and safely from preclinical development to clinical studies. Market launch can thus be significantly accelerated.

Consequently, to improve your cost efficiency and save internal resources, take advantage of our knowledge and experience in synthetic organic chemistry and drug discovery.