Discovery & development of new drugs
Take advantage of our expertise in synthetic organic chemistry for the discovery and development of new drugs to address unmet medical needs.
Feel free to select compound libraries or individual substances directly from our internal stock list. Alternatively, cherry-picked molecules or dedicated series of compounds may also be synthesized de novo on demand.
Reference materials are indispensable for performing the pharmacokinetic studies necessary for the development of innovative drugs.
For high-throughput screening campaigns in medicinal chemistry.
We offer focused and diversified compound libraries and individual small molecules for the early phase of drug discovery & development. Initial test compounds for "hit finding" are either provided from our internal stock or exclusively synthesized. Subsequent hit-to-lead studies and lead optimizations are performed by further chemical structure modifications to increase potency, selectivity, bioavailability and to improve the safety profile.
- Cost-effective development of synthesis methods for the production of compound libraries and individual small molecules, including by-products, impurities and metabolites.
For the development of innovative drugs, reference materials are indispensable for performing the necessary pharmacokinetic studies. It is not uncommon for projects to be significantly delayed or even fail because the required reference standards of active ingredients, metabolites, by-products or impurities are not available quickly enough. Initial test compounds for "hit finding" are either provided from our internal stock or exclusively synthesized. Subsequent hit-to-lead studies and lead optimizations are performed by further chemical structure modifications to increase potency, selectivity, bioavailability and to improve the safety profile.
That is why Endotherm Life Science Molecules supports research-based pharmaceutical companies in the discovery and development of new drugs by independently developing syntheses of the necessary reference materials. This enables your projects to move quickly and safely from preclinical development to clinical studies. Market launch can thus be significantly accelerated.
Consequently, to improve your cost efficiency and save internal resources, take advantage of our knowledge and experience in synthetic organic chemistry and drug discovery.
Complex (fluorescent) dyes
The Endotherm Life Science Molecules portfolio includes complex fluorescent dyes to support new biochemical assays for high-throughput screening campaigns in medicinal chemistry. These include high-value coumarin dyes such as CCF4-AM and 6,8-difluoro-4-methyl-umbelliferyl phosphate (DIFMUP) as well as Lucifer Yellow and 6,6'-dibromo indigo. Click here for the product catalog:
We welcome your project inquiries and will be happy to support you with top-class medicinal chemistry.