{"id":27200,"date":"2022-03-22T15:38:20","date_gmt":"2022-03-22T14:38:20","guid":{"rendered":"https:\/\/endotherm-lsm.com\/auftragssynthesen\/medizinische-chemie"},"modified":"2024-09-06T16:44:37","modified_gmt":"2024-09-06T14:44:37","slug":"medizinische-chemie","status":"publish","type":"page","link":"https:\/\/endotherm-lsm.com\/en\/auftragssynthesen\/medizinische-chemie","title":{"rendered":"Medicinal chemistry"},"content":{"rendered":"\n
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Medicinal chemistry<\/h1>\n<\/div><\/div>\n\n\n\n
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Discovery & development of new drugs<\/h2>\n\n\n\n

Take advantage of our expertise in synthetic organic chemistry for the discovery and development of new drugs to address unmet medical needs.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Screening compounds<\/h4>\n\n\n\n

Feel free to select compound libraries or individual substances directly from our internal stock list. Alternatively, cherry-picked molecules or dedicated series of compounds may also be synthesized de novo<\/em> on demand.<\/p>\n\n\n\n

read more<\/a><\/p>\n<\/div>\n\n\n\n

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Reference materials<\/h4>\n\n\n\n

Reference materials are indispensable for performing the pharmacokinetic studies necessary for the development of innovative drugs.<\/p>\n\n\n\n

read more<\/a><\/p>\n<\/div>\n\n\n\n

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Fluorescent dyes<\/h4>\n\n\n\n

For high-throughput screening campaigns in medicinal chemistry.<\/p>\n\n\n\n

read more<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Screening compounds<\/h2>\n\n\n\n

We offer focused and diversified compound libraries and individual small molecules for the early phase of drug discovery & development. Initial test compounds for \"hit finding\" are either provided from our internal stock or exclusively synthesized. Subsequent hit-to-lead studies and lead optimizations are performed by further chemical structure modifications to increase potency, selectivity, bioavailability and to improve the safety profile.<\/p>\n\n\n\n