{"id":1750,"date":"2022-04-27T16:26:20","date_gmt":"2022-04-27T14:26:20","guid":{"rendered":"https:\/\/endotherm-lsm.com\/publikationen"},"modified":"2025-08-08T14:48:17","modified_gmt":"2025-08-08T12:48:17","slug":"publications","status":"publish","type":"page","link":"https:\/\/endotherm-lsm.com\/en\/profil\/publications","title":{"rendered":"Publications"},"content":{"rendered":"\n<div class=\"wp-block-cover alignfull is-light page__header\" style=\"min-height:300px\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-0 has-background-dim\"><\/span><img decoding=\"async\" loading=\"lazy\" width=\"2437\" height=\"872\" class=\"wp-block-cover__image-background wp-image-4563\" alt=\"\" src=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119.jpg\" style=\"object-position:37% 46%\" data-object-fit=\"cover\" data-object-position=\"37% 46%\" srcset=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119.jpg 2437w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-300x107.jpg 300w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-600x215.jpg 600w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-1024x366.jpg 1024w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-768x275.jpg 768w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-1536x550.jpg 1536w, https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/07\/header-ENDOTHERM_2_2200119-2048x733.jpg 2048w\" sizes=\"(max-width: 2437px) 100vw, 2437px\" \/><div class=\"wp-block-cover__inner-container\">\n<h1 class=\"wp-block-heading page__title has-accent-color has-text-color\">Publications<\/h1>\n<\/div><\/div>\n\n\n\n<div class=\"is-layout-flex wp-container-6 wp-block-columns publications md__padding\">\n<div class=\"is-layout-flow wp-block-column\">\n<h2 class=\"wp-block-heading\"><meta http-equiv=\"content-type\" content=\"text\/html; charset=utf-8\">Publications<\/h2>\n\n\n\n<div class=\"is-layout-flex wp-container-4 wp-block-columns\">\n<div class=\"is-layout-flow wp-block-column text\">\n<h4 class=\"wp-block-heading\">2022-2015<\/h4>\n\n\n\n<div class=\"is-layout-flow wp-block-group publication\"><div class=\"wp-block-group__inner-container\">\n<h5 class=\"wp-block-heading\">2022<\/h5>\n\n\n\n<p>Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, K\u00fcnzel SR, K\u00e4mmerer S, G\u00fcnscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A: Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature Communications 2022;13(1):7648. <br>DOI: 10.1038\/s41467-022-35331-0<br><a href=\"https:\/\/www.nature.com\/articles\/s41467-022-35331-0\">View publication<\/a><\/p>\n\n\n\n<p>Kattner L, Rauch E: Synthesis of 13C Labeled Vitamin D Metabolites for Their Use in LC-MS\/MS: Valuable Tools for Cancer Research and Other Applications. Anticancer Res. 2022;42: 5077-5081. DOI: 10.21873\/anticanres.16016<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/01\/Synthesis-of-13C-Labeled-Vitamin....pdf\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Kattner L: Novel approach to A-ring synthon for Pd-catalyzed synthesis of 1\u03b1-hydroxylated vitamin D metabolites. J Steroid Biochem Mol Biol. 2022;<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/Novel-approach-to-A-ring-synthon-for-Pd-catalyzed-synthesis-of...-main.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Loureiro J, Kattner L, Mouri\u00f1o A: Efficient Asymmetric Synthesis of an A\u2010Ring Synthon for Pd\u2010Catalyzed Preparation of 1\u03b1\u2010Hydroxyvitamin D Metabolites and Analogs. Europ J Org Chem. 2022;<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/Efficient-Asymmetric-Synthesis-of-an-A-Ring-Synthon-for-Pd-Catalyzed-Preparation-of-1a-Hydroxyvitamin-D-Metabolites-and-Analogs-1.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p>Putkaradze N, Abdulmughni A, Ilona K. J\u00f3\u017awik IK, Kattner L, Zapp J, Hutter MC, Frank Hannemann F, Andy-Mark W.H. Thunnissen AMWH, Bernhardt R: Functional and structural characterization of cholesterol-,vitamin D 2 - and D 3 \u2013 hydroxylases from bacillus megaterium. Anticancer Res. 2022;42:2195.<\/p>\n\n\n\n<p class=\"external\">Kattner L: Synthesis of 13C-labelled vitamin D metabolites for their use in LC-MS\/MS applications. Anticancer Res. 2022;42:2203.<\/p>\n\n\n\n<p><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/Isotopically-labeled-compounds.pdf\">Flyer: Isotopically labeled compounds<\/a><\/p>\n\n\n\n<p><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/210319-Unternehmenspra\u0308sentation-Endotherm-deutsch.pdf\">Company Presentation Endotherm<\/a><\/p>\n<\/div><\/div>\n\n\n\n<h5 class=\"wp-block-heading\">2020<\/h5>\n\n\n\n<p class=\"external\">M\u00e4der P, Kattner L: Sulfoximines as Rising Stars in Modern Drug Discovery? Current Status and Perspective on an Emerging Functional Group in Medicinal Chemistry. J. Med. Chem. 2020, 63, 23, 14243\u201314275<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/acs.jmedchem.0c00960.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Kattner L, Rauch E: Efficient synthesis of 3-TBDMS-11\u03b1,25-dihydroxyvitamin D3 and D2 ethers. J Steroid Biochem Mol Biol. 2020;200: 105638.<br><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0960076019305485?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Putkaradze N, K\u00f6nig L, Kattner L, Hutter MC, Bernhardt R: Highly regio- and stereoselective hydroxylation of vitamin D2 by CYP109E1. Biochem Biophys Res Commun 2020;524(2):295-300<br><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0006291X20301601?via%3Dihub\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Kattner L, Rauch E: Recent developments towards the synthesis of vitamin D metabolites. Anticancer Res 2019;39:3280-3281.<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2022\/10\/Anticancer-Res-20222203-2022.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2019<\/h5>\n\n\n\n<p class=\"pdf\">Kattner L: Recent developments towards the synthesis of vitamin D metabolites. Anticancer Res 2020;40:519-525.<br><a rel=\"noreferrer noopener\" href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/01\/Recent-Developments...ANTICANCER-RESEARCH-40-519-525-2020.pdf\" target=\"_blank\">View publication<\/a><\/p>\n\n\n\n<p class=\"pdf\">M\u00e4der P: Boron in Medicinal Chemistry: Powerful, but Neglected, CHIMIA 2019, 73, No. 7\/8<br><a rel=\"noreferrer noopener\" href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/05\/PDF.js-viewer.pdf\" target=\"_blank\">View Publikation<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2018<\/h5>\n\n\n\n<p class=\"external\">Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didi\u00e9 M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K: Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression. Science Translational Medicine 2018;10:eaan0724.<br><a rel=\"noreferrer noopener\" href=\"https:\/\/www.science.org\/doi\/10.1126\/scitranslmed.aan0724\" target=\"_blank\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2017<\/h5>\n\n\n\n<p>Mohamed, B. A., Kattner, L., Guan, K., Lehnart, S. E., Luther, S., Sossalla,S., et al.: The relevant role of SR Ca leak in the development of heart failure. European Journal of Heart Failure 2017; 19(Suppl_1): 343-343.<\/p>\n\n\n\n<p class=\"external\"><br>Kattner L, Bernardi D: An Efficient Synthesis of 1alpha,25-Dihydroxyvitamin D3 LC-Biotin. J Steroid Biochem Mol Biol. 2017;173:89-92.<br><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0960076017300353\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Kattner L, Volmer DA: Synthesis of Low Abundant Vitamin D Metabolites and Assaying Their Distribution in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS\/MS) as a New Tool for Diagnosis and Risk Prediction of Vitamin D related Diseases In: A Critical Evaluation of Vitamin D - Basic Overview, Sivakumar Gowder (editor), Intech publishers, Rijeka. 2017;103-127. ISBN 978-953-51-3084-0.<br><a rel=\"noreferrer noopener\" href=\"https:\/\/www.intechopen.com\/chapters\/52555\" target=\"_blank\">View publication<\/a><\/p>\n\n\n\n<p class=\"pdf\"><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/04\/05-4-seitig-Entwurf-Flyer-2017-2.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Flyer: Your partner for vitamin D synthesis<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2016<\/h5>\n\n\n\n<p class=\"pdf\">Kattner L, Rauch E: Optimization of Chemical Syntheses of Vitamin D C3-Epimers. Anticancer Res 36(3):1417-1422, 2016.<br><a rel=\"noreferrer noopener\" href=\"https:\/\/endotherm-lsm.com\/images\/download\/dokumente\/ANTICANCER_RESEARCH_36_1417-1422_2016.pdf\" target=\"_blank\">View publication<\/a><\/p>\n\n\n\n<p class=\"pdf\">3rd Compass to Europe\u00b4s Innovative Chemical Companies<br><a href=\"https:\/\/ar.iiarjournals.org\/content\/35\/2\/1205\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2015<\/h5>\n\n\n\n<p class=\"pdf\">Kattner L, Bernardi D, Rauch E: Development of Efficient Chemical Syntheses of Vitamin D Degradation Products. Anticancer Res 35(2):1205-1210, 2015.<br><a rel=\"noreferrer noopener\" href=\"https:\/\/endotherm-lsm.com\/images\/download\/2015\/Anticancer_Res_2015_35_2_1205_1210..pdf\" target=\"_blank\">View publication<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"is-layout-flow wp-block-column text\">\n<h4 class=\"wp-block-heading\">2014-2007<\/h4>\n\n\n\n<h5 class=\"wp-block-heading\">2014<\/h5>\n\n\n\n<p class=\"external\">Azimi Hashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF: Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications (5):1-12, 2014.<br><a href=\"https:\/\/www.nature.com\/articles\/ncomms6810\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2013<\/h5>\n\n\n\n<p class=\"external\">Sotoud H, Gribbon P, Ellinger B, Reinshagen J, Boknik P, Kattner L, El-Armouche A, Eschenhagen Th: Development of a Colorimetric and a Fluorescence Phosphatase-Inhibitor Assay Suitable for Drug Discovery Approaches. J Biomol Screen 18(8):899-909, 2013.<br><a href=\"https:\/\/journals.sagepub.com\/doi\/full\/10.1177\/1087057113486000\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Bourgonje VJ, Vos MA, Ozdemir S, Doisne N, Acsai K, Varro A, Sztojkov-Ivanov A, Zupko I, Rauch E, Kattner L, Bito V, Houtman M, van der Nagel R, Beekman JD, van Veen TA, Sipido K, Antoons G: Combined Na+\/Ca2+ Exchanger and L-Type CalciumChannel Block as a Potential Strategy to Suppress Arrhythmias and Maintain Ventricular Function. Circulation: Arrhythm Electrophysiol. 6:371-379, 2013.<br><a href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCEP.113.000322\">View publication<\/a><\/p>\n\n\n\n<p class=\"external\">Scholz T, Heyl CL, Bernardi D, Zimmermann S, Kattner L, Klein CD: Chemical, Biochemical and Microbiological Properties of a Brominated Nitrovinylfuran with Broad-Spectrum Antibacterial Activity. Bioorg Med Chem, 21:795-804, 2013.<br><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0968089612009029\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2009<\/h5>\n\n\n\n<p class=\"external\">Steuer Ch, Heinonen KH, Kattner L, Klein CD: Optimization of assay Conditions for Dengue Virus protease. Effect of various Polyols and Nonionic Detergents. J Biomol Screen. 14(9):1102-1108, 2009.<br><a href=\"https:\/\/journals.sagepub.com\/doi\/abs\/10.1177\/1087057109344115\">View publication<\/a><\/p>\n\n\n\n<p class=\"pdf\">Poster \u201cFrontiers in Medicinal Chemistry\u201d, Heidelberg: Identification of Lead Compounds for Dengue NS3 Protease Inhibitors.<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/04\/Poster-Med-Chem.-HD-Endfassung-Din-A0.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<p>Sotoud H, Kattner L, Eschenhagen Th, El-Armouche A Colorimetric protein phosphatase inhibition assay for specific detection of phosphatase-inhibitor-1 inhibitory compounds Archiv f\u00fcr Experimentelle Pathologie und Pharmakologie 2009.<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2008<\/h5>\n\n\n\n<p class=\"pdf\">Holzer M, Ziegler S, Albrecht B, Kronenberger B, Kaul A, Bartenschlager R, Kattner L, Klein CD, Hartmann RW: Identification of Terfenadine as an Inhibitor of Human CD81-receptor HCV-E2 Interaction: Synthesis and Structure Optimization. Molecules.13:1081-1110, 2008.<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/04\/Molecules-2008-13-1081-1110.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n\n\n\n<h5 class=\"wp-block-heading\">2007<\/h5>\n\n\n\n<p class=\"pdf\">Outsourcing of medicinal chemistry in the drug discovery process faces CRO\u00b4s and pharmaceutical companies with challenges. PharmChem. 2007, July\/August, 6-7.<br><a href=\"https:\/\/endotherm-lsm.com\/wp-content\/uploads\/2023\/04\/PharmaChem-07-08-2007.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">View publication<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Publications 2022-2015 2022 Klapproth E, Witt A, Klose P, Wiedemann J, Vavilthota N, K\u00fcnzel SR, K\u00e4mmerer S, G\u00fcnscht M, Sprott D, Lesche M, Rost F, Dahl A, Rauch E, Kattner L, Weber S, Mirtschink P, Kopaliani I, Guan K, Lorenz K, Saftig P, Wagner M, El-Armouche A: Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early &#8230; <a title=\"Publications\" class=\"read-more\" href=\"https:\/\/endotherm-lsm.com\/en\/profil\/publications\" aria-label=\"Read more about Publications\">Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":27285,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/pages\/1750"}],"collection":[{"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/comments?post=1750"}],"version-history":[{"count":10,"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/pages\/1750\/revisions"}],"predecessor-version":[{"id":64795,"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/pages\/1750\/revisions\/64795"}],"up":[{"embeddable":true,"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/pages\/27285"}],"wp:attachment":[{"href":"https:\/\/endotherm-lsm.com\/en\/wp-json\/wp\/v2\/media?parent=1750"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}